Panadol Cold & Flu Relief tablets relieve discomfort in colds, flu and sore throat and help reduce temperature. They are also used for the relief of headache, migraine, backache, rheumatic pain, muscle pain, neuralgia, toothache and period pain. The tablets contain two active ingredients. Paracetamol is a painkiller and reduces your temperature when you have a fever. Caffeine acts to further help the effectiveness of paracetamol.